Articles co-published by EurOPDX Members
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2017
Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E, Marine JC, Medico E, Norum JH, Palmer HG, Peeper DS, Pelicci PG, Piris-Gimenez A, Roman-Roman S, Rueda OM, Seoane J, Serra V, Soucek L, Vanhecke D, Villanueva A, Vinolo E, Bertotti A, Trusolino L. Interrogating open issues in cancer medicine with patient-derived xenografts. Nature Reviews, Cancer. 2017 Apr;17 (4):254-268.
T.F. Meehan, N. Conte, T. Goldstein, G. Inghirami, M.A. Murakami, S. Brabetz, Z. Gu, J.A. Wiser, P. Dunn, D.A. Begley, D.M. Krupke, A. Bertotti, A. Bruna, M.H. Brush, A.T. Byrne, C. Caldas, A.L. Christie, D.A. Clark, H. Dowst, D.R. Dry, J.H. Doroshow, O. Duchamp, Y.A. Evrard, S. Ferretti, K.K. Frese, N.C. Goodwin, D. Greenawalt, M.A. Haendel, E. Hermans, P.J. Houghton, J. Jonkers, K. Kemper, T.O. Khor, M.T. Lewis, K.C.K Lloyd, J. Mason, E. Medico, S.B. Neuhauser, J.M. Olson, D.S. Peeper, O.M. Rueda, J.K. Seong, L. Trusolino, E. Vinolo, R.J. Wechsler-Reya, D.M. Weinstock, A. Welm, S.J. Weroha, F. Amant, S.M. Pfister, M. Kool, H. Parkinson, A.J. Butte, C.J. Bult. PDX-MI: minimal information for patient-derived tumor xenograft models. Cancer research, 77(21), pp.e62-e66 (2017).
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2016
Alejandra Bruna, Oscar M. Rueda, Wendy Greenwood, Ankita Sati Batra, Maurizio Callari, Rajbir Nath Batra, Katherine Pogrebniak, Jose Sandoval, John W. Cassidy, Ana Tufegdzic-Vidakovic, Stephen-John Sammut, Linda Jones, Elena Provenzano, Richard Baird, Peter Eirew, James Hadfield, Matthew Eldridge, Anne McLaren-Douglas, Andrew Barthorpe, Howard Lightfoot, Mark J. O’Connor, Joe Gray, Javier Cortes, Jose Baselga, Elisabetta Marangoni, Alana L. Welm, Samuel Aparicio, Violeta Serra, Mathew J. Garnett, Carlos Caldas, A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds, Cell, Volume 167, Issue 1, 2016, 260-274.e22
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2015
B.M. Simões, C.S. O'Brien, R.Eyre, A. Silva, L. Yu, A. Sarmiento-Castro, D.G. Alférez, K. Spence, A. Santiago-Gómez, F. Chemi, A. Acar, A. Gandhi, A. Howell, K. Brennan, L. Rydén, S. Catalano, S. Andó, J.J. Gee, A. Ucar, A.H. Sims, E. Marangoni, G. Farnie, G. Landberg, S.J. Howell, R.B. Clarke, Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity. Cell Rep. 12(12):1968-77(2015)
C. García-García, M.A. Rivas, Y.H. Ibrahim, M.T. Calvo, A. Gris-Oliver, O. Rodríguez, J. Grueso, P. Antón, M. Guzmán, C. Aura, P. Nuciforo, K. Jessen, G. Argilés, R. Dienstmann, A. Bertotti, L. Trusolino, J. Matito, A. Vivancos, I. Chicote, H.G. Palmer, J. Tabernero, M. Scaltriti, J. Baselga and V. Serra, MEK plus PI3K/mTORC1/2 Therapeutic Efficacy Is Impacted by TP53 Mutation in Preclinical Models of Colorectal Cancer. Clin. Cancer Res. Aug 13 (2015)
R. Vicario, V. Peg, B. Morancho, M. Zacarias-Fluck, J. Zhang, A. Martínez-Barriocanal, A. Navarro Jiménez, C. Aura, O. Burgues, A. Lluch, J. Cortés, P. Nuciforo, Isabel T. Rubio, E. Marangoni, J. Deeds, M. Boehm, R. Schlegel, J. Tabernero, R. Mosher, J. Arribas, Patterns of HER2 Gene Amplification and Response to Anti-HER2 Therapies. PLoS One. Jun 15;10(6): e0129876 (2015)
E. R. Zanella, F. Galimi, F. Sassi, G. Migliardi, F. Cottino, S. M. Leto, B. Lupo, J. Erriquez, C. Isella, P. M. Comoglio, E. Medico, S. Tejpar, E. Budinska, L. Trusolino, A. Bertotti, IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies. Science translational medicine 7, 272ra212 (2015)
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2014
M. Hidalgo, F. Amant, A. V. Biankin, E. Budinska, A. T. Byrne, C. Caldas, R. B. Clarke, S. de Jong, J. Jonkers, G. M. Maelandsmo, S. Roman-Roman, J. Seoane, L. Trusolino, A. Villanueva, Patient-derived xenograft models: an emerging platform for translational cancer research. Cancer discovery 4, 998-1013 (2014)