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  • REGISTRATION to the 3rd EurOPDX Workshop is OPEN! — Thumbnail image
    22nd Apr, 2022

    REGISTRATION to the 3rd EurOPDX Workshop is OPEN!

    The workshop will be a fully in-person meeting, [b]held on 27-29 June 2022 at the Hotel Zuiderduin in Egmond aan Zee, The Netherlands[/b]. Please visit www.europdxworkshop.eu to know everything about the scientific programme and how to register and submit an abstract. As the first two workshops, we ...

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  • Save the date! 3rd EurOPDX Workshop to be held in the Netherlands on 27-29 June 2022 — Thumbnail image
    7th Mar, 2022

    Save the date! 3rd EurOPDX Workshop to be held in the Netherlands on 27-29 June 2022

    The last EurOPDX Workshop in 2018 feels like ages ago. After two years of COVID-19 pandemic and having postponed the 3 rd edition several times, we are delighted to announce that the next EurOPDX Workshop will be held on 27-29 June 2022 at the Hotel Zuiderduin in Egmond aan Zee, The Netherlands. The...

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  • EurOPDX and PDXNet Consortia publish a milestone paper on PDX reliability — Thumbnail image
    8th Jan, 2021

    EurOPDX and PDXNet Consortia publish a milestone paper on PDX reliability

    CONSERVATION OF COPY NUMBER PROFILES DURING ENGRAFTMENT AND PASSAGING OF PATIENT-DERIVED CANCER XENOGRAFTS Cancer is one of the major causes of death in Europe. Therefore identification, validation and optimisation of therapeutic strategies to improve survival and quality of life of cancer patients ...

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  • Massimiliano Borsani appointed as EurOPDX Research Infrastructure Manager — Thumbnail image
    4th Dec, 2020

    Massimiliano Borsani appointed as EurOPDX Research Infrastructure Manager

    After internal consultation, Prof. Enzo Medico, the Coordinator of the EurOPDX Distributed Infrastructure for Research of patient-derived Xenografts (EDIReX), appointed Dr. Massimiliano Borsani as Research Infrastructure Manager of the project. Massimiliano is the first to hold this new position an...

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  • A unique collection of patient-derived brain tumour models to accelerate drug development  — Thumbnail image
    6th Nov, 2020

    A unique collection of patient-derived brain tumour models to accelerate drug development

    Summary: The NORLUX Neuro-Oncology Laboratory at the Luxembourg Institute of Health (LIH) Department of Oncology, in collaboration with multiple local and international partners, established a large collection of patient-derived glioma organoids and xenograft models that mimic the specific feature...

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  • New major PDX data release & 1 month left to apply for access! — Thumbnail image
    18th Aug, 2020

    New major PDX data release & 1 month left to apply for access!

    We just released a few days ago a new v2.0 version of our repository, the EurOPDX Data Portal. The Portal now displays a total of 995 PDX models with associated metadata and, for many of them, cytogenetics, gene mutation, expression data, copy number alterations, and drug efficacy data. Of these mod...

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  • OPEN CALL for trans-national access to PDX resources and services NOW OPEN! — Thumbnail image
    14th Feb, 2020

    OPEN CALL for trans-national access to PDX resources and services NOW OPEN!

    As part of the EU-funded EDIReX project, we just launched our 3rd and last call for free-of-charge access to the PDX models, resources and expertise of the EurOPDX Research Infrastructure, in the form of an OPEN CALL. The three types of access SAMPLE, DEPOSIT and TEST are available, and hands-on tra...

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  • Meet us at the EORTC-PAMM 2020 Winter Meeting in Stockholm on 13-15 February — Thumbnail image
    31st Jan, 2020

    Meet us at the EORTC-PAMM 2020 Winter Meeting in Stockholm on 13-15 February

    The manager of the EurOPDX Research Infrastructure, Emilie Vinolo (seeding science SRL, Limelette, Belgium), will attend the 41st EORTC-PAMM meeting held in Stockholm on 13th-15th February 2020. She will give a short talk in the afternoon session on Friday 14th February in order to present the EurOP...

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  • Projects begin for successful applicants of our 1st call for Trans-national access! — Thumbnail image
    8th May, 2019

    Projects begin for successful applicants of our 1st call for Trans-national access!

    The 1st call for Trans-national Access (TA) of the EurOPDX Research Infrastructure closed at the beginning of the year. Successful candidates were notified of acceptance of their projects at the end of March 2019, and we are pleased to announce that these projects are now underway, covering a divers...

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  • Registration extended for 10th workshop on Innovative Mouse Models (IMM2019) – 19th to 21st June, 2019 in Leiden, The Netherlands. — Thumbnail image
    8th May, 2019

    Registration extended for 10th workshop on Innovative Mouse Models (IMM2019) – 19th to 21st June, 2019 in Leiden, The Netherlands.

    Between the 19th and 21st of June 2019, the Netherlands Cancer Institute (NKI) and the Leiden University Medical Center (LUMC) organise the 10th edition of the workshop on Innovative Mouse Models (IMM2019) in Leiden, the Netherlands. The goal of IMM2019 is to bring together a diverse group of scien...

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  • EurOPDX at AACR Annual Meeting 2019 — Thumbnail image
    9th Apr, 2019

    EurOPDX at AACR Annual Meeting 2019

    Both the EurOPDX Research Infrastructure and EurOPDX consortium were present at the American Association of Cancer Research (AACR) annual meeting in Atlanta, Georgia, from the 29th March to the 3rd April 2019. The AACR Annual meeting is a renowned forum, covering a full spectrum of cancer research ...

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  • JOB ANNOUNCEMENT – EXCITING OPPORTUNITY FOR A BIOINFORMATICIAN TO WORK WITH OUR PARTNERS AT PDX FINDER (EMBL-EBI, UK). — Thumbnail image
    28th Feb, 2019

    JOB ANNOUNCEMENT – EXCITING OPPORTUNITY FOR A BIOINFORMATICIAN TO WORK WITH OUR PARTNERS AT PDX FINDER (EMBL-EBI, UK).

    Are you a Bioinformatician or data scientist who wants to integrate & mine genomic/phenotypic cancer data? Do you have the skills to research, design, & develop analyses for data of genetic contributors to cancer? If so, then PDX Finder and EMBL-EBI are looking for you! ...

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  • The EurOPDX Research Infrastructure publishes its PDX model Health Monitoring procedure for the wider research community. — Thumbnail image
    22nd Feb, 2019

    The EurOPDX Research Infrastructure publishes its PDX model Health Monitoring procedure for the wider research community.

    The microbiological status of PDX models directly influences both experimental variability and animal welfare. It also imposes a risk to the personnel involved in experimentation. In order to guarantee biosecurity, ensure the quality of the PDX samples, and facilitate the transfer of samples between...

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  • 31st Conference of the International Association for Breast Cancer Research (IABCR 2019) – Registration deadline – 15th March! — Thumbnail image
    21st Feb, 2019

    31st Conference of the International Association for Breast Cancer Research (IABCR 2019) – Registration deadline – 15th March!

    The IABCR 2019 (31st Conference of the International Association for Breast Cancer Research) will be held on April 15-18, 2019 at Hotel Zuiderduin, Egmond aan Zee, The Netherlands. IABCR Conferences are international biannual meetings focusing on the molecular mechanisms underlying breast cancer de...

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  • EurOPDX Data Portal Update - Gastric PDX models added to our collection — Thumbnail image
    8th Feb, 2019

    EurOPDX Data Portal Update - Gastric PDX models added to our collection

    76 Gastric PDX models from the University of Torino, Candiolo Cancer Institute, have now been added to our EurOPDX Data Portal. Our collection now totals 720 PDX models for 3 cancer types. We are continually adding new models, so check back regularly. The EurOPDX Research Infrastructure 1st call f...

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  • EurOPDX Trans-National Access - APPLY FOR ACCESS TO GASTRIC & BREAST PDX MODELS NOW! — Thumbnail image
    24th Jan, 2019

    EurOPDX Trans-National Access - APPLY FOR ACCESS TO GASTRIC & BREAST PDX MODELS NOW!

    ++ UPDATED SAMPLE APPLICATION FORM ++ Now you can apply for access to GASTRIC and BREAST PDX models that are not yet visible on the EurOPDX Data Portal In the updated "Part 3" of the application form, you can now list your desired model(s) by: /cancer type /sub-type /particular molecu...

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  • ONLY 10 DAYS LEFT TO SUBMIT PROPOSALS FOR OUR 1ST CALL FOR SAMPLE & DEPOSIT ACCESS GRANTS — Thumbnail image
    21st Jan, 2019

    ONLY 10 DAYS LEFT TO SUBMIT PROPOSALS FOR OUR 1ST CALL FOR SAMPLE & DEPOSIT ACCESS GRANTS

    We are offering free-of-charge access to the PDX models, resources, and expertise of the EurOPDX Research Infrastructure (EurOPDX RI), as part of the EU-funded EDIReX project. Known as Trans-national Access (TA) grants, we welcome proposals in two forms: 1) SAMPLE – where researchers can request...

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  • 31st Conference of the International Association for Breast Cancer Research (IABCR 2019) – Registration & abstract submission now open! — Thumbnail image
    24th Dec, 2018

    31st Conference of the International Association for Breast Cancer Research (IABCR 2019) – Registration & abstract submission now open!

    The IABCR 2019 (31st Conference of the International Association for Breast Cancer Research) will be held on April 15-18, 2019 at Hotel Zuiderduin, Egmond aan Zee, The Netherlands. IABCR Conferences are international biannual meetings focusing on the molecular mechanisms underlying breast cancer de...

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  • EurOPDX Research Infrastructure Trans-national Access (TA) 1st call for proposals NOW OPEN! — Thumbnail image
    31st Oct, 2018

    EurOPDX Research Infrastructure Trans-national Access (TA) 1st call for proposals NOW OPEN!

    As part of the EU-funded EDIReX project, we are offering free-of-charge access to the PDX models, resources, and expertise of the EurOPDX Research Infrastructure (RI). Known as Trans-national Access (TA) grants, we welcome proposals in two forms:, 1) SAMPLE – where researchers can request PDX mod...

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  • Accelerate your research with CORBEL’s 2nd Open Call for biomedical research projects — Thumbnail image
    22nd Oct, 2018

    Accelerate your research with CORBEL’s 2nd Open Call for biomedical research projects

    The CORBEL1 Open Call invites researchers from academia and industry to apply for access to a wide range of high-end technologies and services from more than 20 facilities across 10 different research infrastructures within Europe. These include state-of-the-art offerings from the fields of advance...

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  • EurOPDX members from VHIO publish promising data for a potential new & safe treatment of HER2+ breast cancer — Thumbnail image
    3rd Oct, 2018

    EurOPDX members from VHIO publish promising data for a potential new & safe treatment of HER2+ breast cancer

    EurOPDX Consortium partners at the Vall d’Hebron Institute of Oncology (VHIO) in Barcelona, Spain, in collaboration with the Roche Innovation Center Zurich and other academic institutions, have developed a novel T-cell bispecific antibody with a potent anti-tumour effect for breast cancer treatmen...

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  • 1 week to go until the 2018 EurOPDX workshop, Are you ready? — Thumbnail image
    24th Sep, 2018

    1 week to go until the 2018 EurOPDX workshop, Are you ready?

    The 2018 EurOPDX workshop is nearly upon us. We excited to welcome attendees from 19 countries, and are pleased to announce that we have a full house this year! All you need to know about this 2nd edition of the EurOPDX workshop can be found on the event website: www.europdxworkshop.eu In addition...

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  • New vacancy for an animal technician at KU Leuven with the TRACE platform — Thumbnail image
    24th Jul, 2018

    New vacancy for an animal technician at KU Leuven with the TRACE platform

    TRACE, a multidisciplinary project focused on the development of Patient-Derived Xenograft (PDX) models, is set up within the department of Oncology at the KU Leuven and it is part of the Leuvens Kankerinstitute (LKI, uzleuven-kuleuven.be). The platform was created in 2012 aiming to narrow the gap b...

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  • Registration for the 2nd EurOPDX Workshop on October 1-3 has now closed! — Thumbnail image
    16th Jul, 2018

    Registration for the 2nd EurOPDX Workshop on October 1-3 has now closed!

    Registration for the second edition of the EurOPDX Workshop has now closed. We are happy to announce that we will have a full house in October. We look forward to welcoming all attendees to beautiful Weggis, Switzerland for what promises to be a fascinating meeting. To see our invited speaker li...

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  • Special focus: the gastric carcinoma PDX collection established at the University of Turin — Thumbnail image
    7th May, 2018

    Special focus: the gastric carcinoma PDX collection established at the University of Turin

    The team of Prof. Silvia Giordano and Dr. Simona Corso at the Department of Oncology, University of Torino/Candiolo Cancer Institute, FPO-IRCCS (Candiolo, Italy) have, over the past few years, established a unique collection of gastric carcinoma PDX models. Gastric tumour samples and matched normal...

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  • Introducing EDIReX: a 5 million EUR infrastructure H2020 project for access to PDX models  — Thumbnail image
    20th Apr, 2018

    Introducing EDIReX: a 5 million EUR infrastructure H2020 project for access to PDX models

    EDIReX, a four-year project funded as part of the EU Horizon2020 Research and Innovation Program (grant agreement no #731105), kicked-off earlier this year and was introduced by project coordinator Prof. Enzo Medico at the 2018 AACR annual meeting in Chicago. EDIReX stands for “EurOPDX Distribute...

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  • WONDERING WHAT'S UP WITH EUROPDX? PRESENTATION OF OUR EDIREX EU PROJECT AT NEXT AACR MEETING! — Thumbnail image
    6th Apr, 2018

    WONDERING WHAT'S UP WITH EUROPDX? PRESENTATION OF OUR EDIREX EU PROJECT AT NEXT AACR MEETING!

    You may be wondering what we have been working at the past few months, as we have been quite silent at least on the website. Well, if you have the chance to attend the AACR meeting this year (April 14-18 in Chicago, Illinois USA), you will get a chance to know more about it. Prof. Enzo Medico (Univ...

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  • COLOSSUS project: EU H2020 grant for research into colorectal cancer awarded to team led by EurOPDX members  — Thumbnail image
    1st Jan, 2018

    COLOSSUS project: EU H2020 grant for research into colorectal cancer awarded to team led by EurOPDX members

    EurOPDX members RCSI, UNITO and VHIO are key partners in a new international research study “COLOSSUS”, which aims to provide novel and more effective ways to classify and treat patients with a specific type of colorectal cancer (MSS RAS mt CRC). The team has secured approximately €6 million ...

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  • **SAVE THE DATE** - 2nd EurOPDX Workshop, Weggis, Switzerland on October 1-3, 2018 — Thumbnail image
    17th Nov, 2017

    **SAVE THE DATE** - 2nd EurOPDX Workshop, Weggis, Switzerland on October 1-3, 2018

    We are delighted to announce that the second edition of the EurOPDX Workshop will be held on October 1-3, 2018 at the same venue in Weggis, Switzerland. Although we are keeping a similar size (100-120 attendees), the format may evolve from the first edition to take into account the feedback received...

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  • EurOPDX members awarded ITN grant to train a new generation of brain cancer researchers — Thumbnail image
    7th Oct, 2017

    EurOPDX members awarded ITN grant to train a new generation of brain cancer researchers

    Glioblastoma (GBM), an aggressive and devastating form of brain tumour, will be the focus of the new four-year project GLIOTRAIN just awarded a 3.9 million euros grant from the European Commission’s Horizon 2020 Marie Sklodowska-Curie Innovative Training Network (ITN) initiative. The project, co-o...

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  • Trace PDX platform at KU Leuven looking for Project Manager/Coordinator — Thumbnail image
    12th May, 2017

    Trace PDX platform at KU Leuven looking for Project Manager/Coordinator

    Trace (http://www.uzleuven-kuleuven.be/lki/trace), a multidisciplinary project focused on patient-derived xenograft (PDX) models at the KU Leuven, is set up within the department of oncology to narrow the gap between preclinical and clinical research by developing a more reliable and predictive in v...

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  • EC Scientific Conference 'Non-Animal Approaches - The Way Forward: we were there! — Thumbnail image
    8th Dec, 2016

    EC Scientific Conference 'Non-Animal Approaches - The Way Forward: we were there!

    We presented a poster at the scientific conference organised by the European Commission in Brussels on December 6-7, 2016 to engage the scientific community and relevant stakeholders in a debate on how to exploit cutting edge advances in biomedical and other research in the development of scientific...

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  • Poster presented at the 1st EurOPDX Workshop with an update on our activities  — Thumbnail image
    4th Oct, 2016

    Poster presented at the 1st EurOPDX Workshop with an update on our activities

    Our first workshop taking place in Weggis, Switzerland on October 3-5 was also an opportunity to present a poster with an update on the current members of the Consortium, our objectives, achievements so far and future directions. You can upload this poster using the following link: https://www.drop...

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  • Featured Cell article - Breast cancer PDX-derived cells as drug-screening platform — Thumbnail image
    15th Sep, 2016

    Featured Cell article - Breast cancer PDX-derived cells as drug-screening platform

    Alejandra Bruna and colleagues, from Prof. Carlos Caldas laboratory at the Cancer Research UK Cambridge Institute (CI), recently published in Cell a new experimental platform using patient-derived tumour xenografts (PDTXs) of breast cancer (BC) in high-content preclinical drug screening. This work r...

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  • EurOPDX Workshop 2016: Abstract submission deadline pushed to July 14, it's your lucky day! — Thumbnail image
    1st Jul, 2016

    EurOPDX Workshop 2016: Abstract submission deadline pushed to July 14, it's your lucky day!

    It's your lucky day: we have decided to postpone the abstract submission deadline until July 14! You will find all necessary information on the Workshop “PDX models in clinical oncology and cancer precision medicine" on the dedicated webpage: http://www.europdxworkshop2016.eu/ Registration w...

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  • EurOPDX Workshop 2016: Registration now open, don't miss the June 30 deadline! — Thumbnail image
    24th Jun, 2016

    EurOPDX Workshop 2016: Registration now open, don't miss the June 30 deadline!

    Registration is now open for our Workshop “PDX models in clinical oncology and cancer precision medicine”, taking place in Weggis, Stwitzerland on October 3-5, 2016. You will find all necessary information on the workshop webpage: http://www.europdxworkshop2016.eu/ For any question you might ...

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  • Weill Cornell Medical College in New York joining the EurOPDX Consortium — Thumbnail image
    4th Apr, 2016

    Weill Cornell Medical College in New York joining the EurOPDX Consortium

    The EurOPDX Consortium is now reaching out to the US, with the Board of Coordinators having very recently voted for Weill Cornell Medical College (WCM) in New York (NY, USA) to join. Our collaboration with WCM started a few months ago for the set-up of an instance of the cBioPortal dedicated to PDX...

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  • 11th Feb, 2016

    **SAVE THE DATE** - EurOPDX Workshop, Weggis, Switzerland on October 3-5, 2016

    We are very excited to announce the organisation of a workshop on "PDX models to interrogate open issues in clinical oncology and cancer precision medicine", which will take place in Weggis, Switzerland on October 3-5, 2016. This educational workshop will feature speakers from the Consorti...

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  • 27th Nov, 2015

    3 years & a new name for the Leuven PDX platform: Trace

    On November 27, 2015 we have been celebrating with a PDX Symposium the 3rd anniversary of the PDX platform in the University Hospitals Leuven and Katholieke Universiteit Leuven. Several researchers from Leuven and other institutions have been presenting their work on the establishment and validation...

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  • 10th Oct, 2015

    Meet EurOPDX members at the AACR PDX meeting in New Orleans in February 2016

    The upcoming Special Conference of the American Association for Cancer Research "Patient-Derived Cancer Models: Present and Future Applications from Basic Science to the Clinic" (New Orleans, February 11-14, 2016) will be co-chaired by our two members Manuel Hidalgo (CNIO, Madrid, Spain) a...

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  • 25th Mar, 2015

    Celebrating 2 years of EurOPDX Consortium in Leuven

    Hosted by the Katholieke Universiteit in Leuven, Belgium, the EurOPDX community recently gathered in order to celebrate the second anniversary of the consortium creation. In a warm atmosphere, this new meeting was an opportunity to review the many achievements of the network since it was initiated t...

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  • 30th Jan, 2015

    A new publication benefitting from EurOPDX networking activities

    The Adrea Bertotii, Livio Trusolino and Enzo Medico group just published a very nice work in Science Translational Medicine (Andrea Bertotii et al. Sci Transl Med 28 January 2015 7:272ra12. DOI:10.1126/scitranslmed.3010445) (http://stm.sciencemag.org/content/7/272/272ra12.abstract?sid=ae24ed4a-9b05-...

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  • 17th Nov, 2014

    EurOPDX workshop on validation and characterisation of PDX models

    Hosted by the Vall d'Hebron Institute of Oncology (VHIO) in Barcelona, Spain, the EurOPDX community met in November 2014 for the 5th time. This meeting was an opportunity to review the progress of the different collaborative projects pursued by the Consortium. But the main objective was to discuss a...

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  • 1st Jul, 2014

    Watch out for the first publication of the Consortium

    The EurOPDX Consortium just published a very comprehensive review in Cancer Discovery (Hidalgo, M. et al. Cancer Discov; 4(9); 998–1013; http://www.ncbi.nlm.nih.gov.gate2.inist.fr/pubmed/?term=25185190). This article summarises the current state of the art in the field of PDX models, including met...

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  • 1st Apr, 2014

    EurOPDX participation to the AACR 2014 Methods Workshop on PDX

    Scientists of the EurOPDX Consortium will be major contributors to the upcoming "Applications of Patient Derived Xenograft Models to Translational Cancer Research". This workshop will indeed be chaired by Dr. Manuel Hidalgo (CNIO, Madrid, Spain) and will feature a presentation by Dr. Andre...

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  • 13th Oct, 2013

    Meet us at the AACR-NCI-EORTC meeting in Boston (Poster #A8)

    For the first time, the project of the EurOPDX Consortium will be presented as a poster at the next AACR-NCI-EORTC meeting in Boston, by its project manager Emilie Vinolo. Come and let us introduce you our project at the poster session!...

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The EDIReX project has received funding from the European Union’s Horizon 2020 research and innovation programme, grant agreement no. #731105

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